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Antihistamines are inhibitors of histamine receptors. H1-antihistamines, inhibit competitively H1 receptors and the corresponding effects i. They do not inhibit antigen/antibodies reactions, nor histamine release, they inhibit H1 effects. H1-antihistamines have been used for more than fifty years in treating various allergic manifestations. H1-antihistamines which penetrate into brain elicit, by inhibiting stimulant effect of histamine, drowsiness.

A biomedical writer since 2008, she has interviewed countless medical experts in a broad range of subjects, from addiction treatment to pediatric injuries to mind-body medicine for wellness.

To get a good idea of what histamine can do, let us imagine the effects of an injection of a small amount of histamine: Headache is felt as a pulsating, whole-head pain, often with a sense of pressure.

Fast heart, blood pressure falls, irregular beats with alarming palpitations.

Almost everyone has taken an antihistamine to treat hay fever, itching, to relieve nausea and vomiting, in tablets and syrups used to treat cough and cold symptoms, or as an aid to sleep.

The popularity of antihistamines is a mute testimony to the diverse negative effects of histamine.